Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G004211`

染色体: Chr08 坐标: 51505533-51509465 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G004211`
名称	SmilChr08G004211
描述	wall-associated receptor kinase-like 8
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	51505533 - 51509465 / `+`

ID 对照

NCBI Gene ID	`LOC130998943`
GeneID	`130998943`
locus_tag	`-`
NCBI Name	`LOC130998943`
原始查询	`SmilChr08G004211`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	wall-associated receptor kinase-like 8
产物	wall-associated receptor kinase-like 8
Arabidopsis	`AT1G16260` (AT1G16260) Wall-associated kinase family protein [Source:NCBI gene (formerly Entrezgene);Acc:838195] identity=41.4; qcov=1.02; evalue=5.96e-177; confidence=medium
Rice	`Os02g0807800` (OsWAK20) - identity=38.7; qcov=1.04; evalue=1.87e-152; confidence=medium
GO	GO:0004674 (protein serine/threonine kinase activity); GO:0005509 (calcium ion binding); GO:0005524 (ATP binding); GO:0005886 (plasma membrane); GO:0006468 (protein phosphorylation); GO:0007166 (cell surface receptor signaling pathway); GO:0030247 (polysaccharide binding)
KEGG	-
Pfam	PF00069 (Pkinase); PF07714 (PK_Tyr_Ser-Thr); PF13947 (GUB_WAK_bind)
InterPro	-
eggNOG	-
NR	GeneID:130998943

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057780364.1`
2	Nucleus	细胞核	0.00000	`XP_057780364.1`
3	Chromosome	染色体	0.00000	`XP_057780364.1`
4	Centromere	着丝粒	0.00000	`XP_057780364.1`
5	Chromatin	染色质	0.00000	`XP_057780364.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:51507036`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B36
`Chr8:51507134`	`A`	`AC`	1bp_insertion	frameshift_variant	29	A2,A24,A4,A6,B109,B111,B120,B123,B124,B13,B136,B139,B21,B32,B41,B44,B53,B73,B82,B85,C24,C29,C48,C50,C52,C61,C75,C8,D7
`Chr8:51507195`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr8:51507211`	`T`	`TGA`	2bp_insertion	stop_gained,frameshift_variant	1	B139
`Chr8:51507211`	`T`	`TGA`	2bp_insertion	CDS_variant	1	B139
`Chr8:51507314`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B104,B44
`Chr8:51507372`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A18,B76
`Chr8:51507425`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B45,B77,B84,C19,C83
`Chr8:51507469`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C22
`Chr8:51507706`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B80
`Chr8:51507726`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr8:51507736`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B104,B44

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057780364.1

746 aa

373

746

GUB_WAK_bind

Pkinase

PK_Tyr_Ser-Thr

PF13947 GUB_WAK_bind 36-91 aa PF00069 Pkinase 417-681 aa PF07714 PK_Tyr_Ser-Thr 420-684 aa

XP_057780365.1

740 aa

370

740

GUB_WAK_bind

Pkinase

PK_Tyr_Ser-Thr

PF13947 GUB_WAK_bind 30-85 aa PF00069 Pkinase 411-675 aa PF07714 PK_Tyr_Ser-Thr 414-678 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057780364.1`	Pfam	`PF13947`	GUB_WAK_bind	Domain	36	91	2e-09	38.4	Wall-associated receptor kinase galacturonan-binding
`XP_057780364.1`	Pfam	`PF00069`	Pkinase	Domain	417	681	8.3e-50	170.3	Protein kinase domain
`XP_057780364.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	420	684	3e-48	165.1	Protein tyrosine and serine/threonine kinase
`XP_057780365.1`	Pfam	`PF13947`	GUB_WAK_bind	Domain	30	85	2e-09	38.4	Wall-associated receptor kinase galacturonan-binding
`XP_057780365.1`	Pfam	`PF00069`	Pkinase	Domain	411	675	8.2e-50	170.3	Protein kinase domain
`XP_057780365.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	414	678	3e-48	165.1	Protein tyrosine and serine/threonine kinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057924381.1
ACAAAACTTAACCACAAAAGTAGAAATAATTGAGCTCATGAACTCGCAGACAGAAAAGGAAACTCCGATGAACCTGCAGTCGTGCTAAAATTGGCGGTGTTTGGGATTGATAAAGAATCATAAACCTCAGTCGAGATGGCAGCAGGCTCTGTTTCTTCATCACAAGTTTGCAGATTCGCGACCAATTTCCGTATTTGGATTGCTTCCAACTCCATCACCGCTTCCTTCATCGTTGTGCCTTTGCTCACTGTCAAACTCAG...

XM_057924382.1
GAATGATACATAATTTAAGAGTTTGACACAGTCTTAATTACACCAAAGTAGACCACTGTGTTGTCTATTTCAACAGATAAATAATGTCCTCTACACACACACACACATTCAATTGCATTGATTGCTGCTCCATACTCATAGTCAATCTTCAGCACATACGATACGATTCATTGATCAATAACAGGATTTCCTAACGCAAGAGAAAAATGAGGTTGATGCTGCAAATTGTATTGCTATTGTTGTTAATGTTATATACAAGA...

CDS

2 records

下载 CDS FASTA

LOC130998943
ATGGAAGAACAGAGAAAAATGAGGTTGATGCTGCAAATTGTATTGCTATTGTTGTTAATGTTATATACAAGAATGGGTGGAGGGGAGTCCCTGTCGAAGCCCGGTTGCCCCGACACATGTGGAAACAATGTCACGATCCCGTACCCTTTTGGCATCGGTGCAGAGTGCAGCGCCAACGAATACTTCAGAGTGGCGTGCGACAACACGACCAACCCCCCAAAGCCATTCTTGGAGTACATGAGCTTGGAAGCGCTCGAATT...

LOC130998943
ATGAGGTTGATGCTGCAAATTGTATTGCTATTGTTGTTAATGTTATATACAAGAATGGGTGGAGGGGAGTCCCTGTCGAAGCCCGGTTGCCCCGACACATGTGGAAACAATGTCACGATCCCGTACCCTTTTGGCATCGGTGCAGAGTGCAGCGCCAACGAATACTTCAGAGTGGCGTGCGACAACACGACCAACCCCCCAAAGCCATTCTTGGAGTACATGAGCTTGGAAGCGCTCGAATTCTCGTTGGACAGGAAGGT...

Protein

2 records

下载 Protein FASTA

XP_057780364.1
MEEQRKMRLMLQIVLLLLLMLYTRMGGGESLSKPGCPDTCGNNVTIPYPFGIGAECSANEYFRVACDNTTNPPKPFLEYMSLEALEFSLDRKVVRLLQGVFPINCSTNTVILVGKTVSRSTPFRYSSLYNRLVVIGCGNEVRMLDYDTTNGRIPSFGGCNPICGSTSPSCNGINCCQTTLPSLFEEAEVFYNSTGNGRAGSVCGYTFFSDQRWLERDYFRYLNRSGGNWTSFLLEMSSGMTVPLILEWELDVSNATTSLQ...

XP_057780365.1
MRLMLQIVLLLLLMLYTRMGGGESLSKPGCPDTCGNNVTIPYPFGIGAECSANEYFRVACDNTTNPPKPFLEYMSLEALEFSLDRKVVRLLQGVFPINCSTNTVILVGKTVSRSTPFRYSSLYNRLVVIGCGNEVRMLDYDTTNGRIPSFGGCNPICGSTSPSCNGINCCQTTLPSLFEEAEVFYNSTGNGRAGSVCGYTFFSDQRWLERDYFRYLNRSGGNWTSFLLEMSSGMTVPLILEWELDVSNATTSLQGVKCMN...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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