Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G004296`

染色体: Chr08 坐标: 52647770-52656320 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G004296`
名称	SmilChr08G004296
描述	DExH-box ATP-dependent RNA helicase DExH12-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	52647770 - 52656320 / `+`

ID 对照

NCBI Gene ID	`LOC130999025`
GeneID	`130999025`
locus_tag	`-`
NCBI Name	`LOC130999025`
原始查询	`SmilChr08G004296`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	DExH-box ATP-dependent RNA helicase DExH12-like
产物	DExH-box ATP-dependent RNA helicase DExH12-like
Arabidopsis	`AT1G20960` (emb1507) U5 small nuclear ribonucleoprotein helicase [Source:NCBI gene (formerly Entrezgene);Acc:838690] identity=81.1; qcov=0.999; evalue=0; confidence=high
Rice	`Os03g0743800` - identity=69.2; qcov=1.01; evalue=0; confidence=high
GO	GO:0003676 (nucleic acid binding); GO:0005524 (ATP binding); GO:0005634 (nucleus); GO:0016887 (ATP hydrolysis activity)
KEGG	smil03040 (Spliceosome - Salvia miltiorrhiza (redroot sage))
Pfam	PF00270 (DEAD); PF00271 (Helicase_C); PF02889 (Sec63); PF04851 (ResIII); PF18149 (Helicase_PWI); PF21188 (BRR2_plug); PF23445 (WHD_SNRNP200)
InterPro	-
eggNOG	-
NR	GeneID:130999025

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057780481.1`
2	Nucleoplasm	核质	1.00000	`XP_057780481.1`
3	Chromosome	染色体	0.00000	`XP_057780481.1`
4	Centromere	着丝粒	0.00000	`XP_057780481.1`
5	Chromatin	染色质	0.00000	`XP_057780481.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:52648994`	`C`	`CTA`	2bp_insertion	frameshift_variant	1	A1
`Chr8:52648994`	`C`	`CTA`	2bp_insertion	CDS_variant	1	A1
`Chr8:52649330`	`C`	`T`	EMS_canonical_SNV	stop_gained	2	B44,B52
`Chr8:52649330`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B44,B52
`Chr8:52649359`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B34,B98,B99,C83
`Chr8:52649360`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B34,B98,B99,C83
`Chr8:52649366`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B44,B52,B68,C15,C53
`Chr8:52649396`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B51,B80
`Chr8:52649402`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B51,B80
`Chr8:52649429`	`CTT`	`C`	2bp_deletion	frameshift_variant	2	B51,B80
`Chr8:52649429`	`CTT`	`C`	2bp_deletion	CDS_variant	2	B51,B80
`Chr8:52649476`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B84,C29,C81

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057780481.1

2172 aa

1086

2172

BRR2_plug

Helicase_PWI

ResIII

DEAD

Helicase_C

WHD_SNRNP200

Sec63

ResIII

DEAD

WHD_SNRNP200

Sec63

PF21188 BRR2_plug 117-183 aa PF18149 Helicase_PWI 269-378 aa PF04851 ResIII 508-682 aa PF00270 DEAD 509-686 aa PF00271 Helicase_C 798-885 aa PF23445 WHD_SNRNP200 916-992 aa PF02889 Sec63 1008-1311 aa PF04851 ResIII 1351-1513 aa PF00270 DEAD 1354-1525 aa PF23445 WHD_SNRNP200 1754-1835 aa PF02889 Sec63 1841-2158 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057780481.1`	Pfam	`PF21188`	BRR2_plug	Domain	117	183	4.4e-10	40.5	Pre-mRNA-splicing helicase BRR2 plug domain
`XP_057780481.1`	Pfam	`PF18149`	Helicase_PWI	Domain	269	378	1.2e-33	116.4	N-terminal helicase PWI domain
`XP_057780481.1`	Pfam	`PF04851`	ResIII	Family	508	682	5.1e-29	102.0	Type III restriction enzyme, res subunit
`XP_057780481.1`	Pfam	`PF00270`	DEAD	Domain	509	686	9.6e-69	231.1	DEAD/DEAH box helicase
`XP_057780481.1`	Pfam	`PF00271`	Helicase_C	Domain	798	885	5e-16	59.6	Helicase conserved C-terminal domain
`XP_057780481.1`	Pfam	`PF23445`	WHD_SNRNP200	Domain	916	992	8.1e-65	215.7	Winged Helix-turn-helix domain
`XP_057780481.1`	Pfam	`PF02889`	Sec63	Family	1008	1311	1.4e-177	588.7	Sec63 Brl domain
`XP_057780481.1`	Pfam	`PF04851`	ResIII	Family	1351	1513	5.1e-29	102.0	Type III restriction enzyme, res subunit
`XP_057780481.1`	Pfam	`PF00270`	DEAD	Domain	1354	1525	9.6e-69	231.1	DEAD/DEAH box helicase
`XP_057780481.1`	Pfam	`PF23445`	WHD_SNRNP200	Domain	1754	1835	8.1e-65	215.7	Winged Helix-turn-helix domain
`XP_057780481.1`	Pfam	`PF02889`	Sec63	Family	1841	2158	1.4e-177	588.7	Sec63 Brl domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057924498.1
GCCCTTTTGGAAATGAAATAACAACAAACTTAGCAATTGAAAAAAAAAATCAAAACCTTATGGAAATAAACGAGTTATCGCACTCTCGCACTCTTTGTTTCTAACCTTCTTAAACCCTAATTCCCCTTCTCCCTCATCTGCATCTTCAATTCCATAGCTTGGGGACACAGCAGCAAGATTGAAGAAGAGGGAACCTTGTTAACTGTTGACGGGCAAGATGGCTCATCCAGGTGGCGGAGCTGAAGCGCATGCTCGGTTCA...

CDS

1 records

下载 CDS FASTA

LOC130999025
ATGGCTCATCCAGGTGGCGGAGCTGAAGCGCATGCTCGGTTCAAGCAGTATGAGTACAGAGCAAACTCGAGTCTTGTTCTTACCACGGACTCTCGACCTCGTGACACCCATGAGCCAACTGGGGAGCCAGAGTCATTGTGGGGGAAGATTGACCCTAAATCCTTCGGTGACAGGGCATACAGGGATAAACCTCCTGAGTTGGAGGAGAAGCTTAAGAAATCTAAAAAGAAGAAGGAGCGGGAGCCTGCTCTTGATGCTGC...

Protein

1 records

下载 Protein FASTA

XP_057780481.1
MAHPGGGAEAHARFKQYEYRANSSLVLTTDSRPRDTHEPTGEPESLWGKIDPKSFGDRAYRDKPPELEEKLKKSKKKKEREPALDAAPPRSKKRRLQEESVLTSSDEGVYQPKTKETRAAYEAMLSVIQQQLGGQPLNIVSGAADEILAVLKNETIKNPEKKKEIEKLLNPITSTTFDNLVSLGKRITDYHDGGDAGDTAVNRDDGLDDDVGVAVEFEENEEEEEESDLDMVPEDEEDDDDVTEVDGSGAMQMGGIDDDE...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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