Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G004824`

染色体: Chr08 坐标: 57502160-57507220 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G004824`
名称	SmilChr08G004824
描述	receptor-like kinase TMK4
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	57502160 - 57507220 / `+`

ID 对照

NCBI Gene ID	`LOC130999482`
GeneID	`130999482`
locus_tag	`-`
NCBI Name	`LOC130999482`
原始查询	`SmilChr08G004824`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	receptor-like kinase TMK4
产物	receptor-like kinase TMK4
Arabidopsis	`AT3G23750` (AT3G23750) Leucine-rich repeat protein kinase family protein [Source:NCBI gene (formerly Entrezgene);Acc:821957] identity=52.6; qcov=0.988; evalue=0; confidence=high
Rice	`Os03g0717000` (OsTMK) - identity=47.5; qcov=0.972; evalue=0; confidence=high
GO	GO:0004672 (protein kinase activity); GO:0005515 (protein binding); GO:0005524 (ATP binding); GO:0006468 (protein phosphorylation)
KEGG	smil04075 (Plant hormone signal transduction - Salvia miltiorrhiza (redroot sage))
Pfam	PF00069 (Pkinase); PF00560 (LRR_1); PF07714 (PK_Tyr_Ser-Thr); PF08263 (LRRNT_2); PF12799 (LRR_4); PF13855 (LRR_8)
InterPro	-
eggNOG	-
NR	GeneID:130999482

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057781002.1`
2	Nucleus	细胞核	0.00000	`XP_057781002.1`
3	Chromosome	染色体	0.00000	`XP_057781002.1`
4	Centromere	着丝粒	0.00000	`XP_057781002.1`
5	Chromatin	染色质	0.00000	`XP_057781002.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:57502186`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B103,C47,C74,C76
`Chr8:57502191`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B104,C61
`Chr8:57502220`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B105,B95
`Chr8:57502221`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A24,B109,B40,C60,C62
`Chr8:57502249`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B66
`Chr8:57502330`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	D10,D11
`Chr8:57502334`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B105,B95
`Chr8:57502391`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C8
`Chr8:57502415`	`C`	`T`	EMS_canonical_SNV	stop_gained	165	A1,A13,A14,A15,A16,A18,A2,A20,A22,A23,A24,A5,A6,A7,A9,B10,B101,B102,B103,B104,B105,B106,B107,B108,B109,B11,B110,B111,B113,B114,B117,B118,B119,B120,B121,B122,B124,B126,B128,B130,B131,B134,B136,B137,B14,B16,B18,B2,B22,B25,B26,B27,B3,B30,B34,B35,B38,B4,B40,B41,B42,B43,B44,B47,B49,B5,B50,B54,B56,B60,B64,B65,B66,B67,B69,B7,B71,B73,B77,B78,B79,B8,B80,B82,B83,B84,B85,B88,B93,B94,B96,B97,B98,C1,C10,C12,C13,C14,C16,C17,C18,C19,C2,C20,C24,C26,C27,C28,C29,C3,C30,C32,C33,C34,C36,C37,C38,C4,C40,C41,C42,C43,C45,C46,C47,C48,C5,C50,C51,C52,C54,C55,C57,C59,C6,C60,C61,C62,C66,C68,C69,C7,C71,C73,C74,C75,C77,C78,C79,C8,C80,C81,C82,C83,C85,C86,C87,C9,D1,D10,D2,D3,D4,D8,D9
`Chr8:57502474`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B41
`Chr8:57502528`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B105,B95
`Chr8:57502954`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B103,C74,C76

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057781002.1

899 aa

450

899

LRRNT_2

LRR_1

LRRNT_2

LRR_8

LRR_4

LRR_1

Pkinase

PK_Tyr_Ser-Thr

PF08263 LRRNT_2 43-61 aa PF00560 LRR_1 258-279 aa PF08263 LRRNT_2 322-359 aa PF13855 LRR_8 377-422 aa PF12799 LRR_4 386-426 aa PF00560 LRR_1 387-409 aa PF00560 LRR_1 411-428 aa PF00069 Pkinase 570-777 aa PF07714 PK_Tyr_Ser-Thr 572-789 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057781002.1`	Pfam	`PF08263`	LRRNT_2	Family	43	61	1.1e-07	32.8	Leucine rich repeat N-terminal domain
`XP_057781002.1`	Pfam	`PF00560`	LRR_1	Repeat	258	279	3.5e-17	59.5	Leucine Rich Repeat
`XP_057781002.1`	Pfam	`PF08263`	LRRNT_2	Family	322	359	1.1e-07	32.8	Leucine rich repeat N-terminal domain
`XP_057781002.1`	Pfam	`PF13855`	LRR_8	Repeat	377	422	3.2e-17	62.8	Leucine rich repeat
`XP_057781002.1`	Pfam	`PF12799`	LRR_4	Repeat	386	426	4e-21	75.3	Leucine Rich repeats (2 copies)
`XP_057781002.1`	Pfam	`PF00560`	LRR_1	Repeat	387	409	3.5e-17	59.5	Leucine Rich Repeat
`XP_057781002.1`	Pfam	`PF00560`	LRR_1	Repeat	411	428	3.5e-17	59.5	Leucine Rich Repeat
`XP_057781002.1`	Pfam	`PF00069`	Pkinase	Domain	570	777	9.9e-46	157.0	Protein kinase domain
`XP_057781002.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	572	789	2.7e-46	158.7	Protein tyrosine and serine/threonine kinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057925019.1
ATGCCTAGAGGGAGACACAAATTCCTCCCCTCCGACGTCGTTCTCTTAACGACGCTGCTCGCGGCCATCATCCGCCATGCTTCCTGCGACGACGGAGCTGTCATGGCCAAGCTGGCCAAAGCCACCAACCCACCCGGCTGGACTGGCACCGATTTCTGCAAATGGGACGGCGTCGCCTGCGATTCGCCCGGCAGAGTCAGCTCCATCAACCTTGCATCGAAATCCCTCTCTGGAACATTGCCACCTGAGATCAACCAGCT...

CDS

1 records

下载 CDS FASTA

LOC130999482
ATGCCTAGAGGGAGACACAAATTCCTCCCCTCCGACGTCGTTCTCTTAACGACGCTGCTCGCGGCCATCATCCGCCATGCTTCCTGCGACGACGGAGCTGTCATGGCCAAGCTGGCCAAAGCCACCAACCCACCCGGCTGGACTGGCACCGATTTCTGCAAATGGGACGGCGTCGCCTGCGATTCGCCCGGCAGAGTCAGCTCCATCAACCTTGCATCGAAATCCCTCTCTGGAACATTGCCACCTGAGATCAACCAGCT...

Protein

1 records

下载 Protein FASTA

XP_057781002.1
MPRGRHKFLPSDVVLLTTLLAAIIRHASCDDGAVMAKLAKATNPPGWTGTDFCKWDGVACDSPGRVSSINLASKSLSGTLPPEINQLSGLKTLSLQRNKFSGPLPALSNMASLQEVNLEENGFTSIPTGFLSGLTSLQFFSINNNSNLPPWTMPTTIKDSPSLTTFYASKANMVGEIPDIFGSLPNFANLKISYNNLTGWLPWSFSKSGIQTLLLNNQMVGLSGPIDVIGEMHSLREVWLHSNQFTGSIPDLSACTELSD...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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