Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G004952`

染色体: Chr08 坐标: 58377994-58379105 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G004952`
名称	SmilChr08G004952
描述	E3 ubiquitin-protein ligase SIRP1
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	58377994 - 58379105 / `-`

ID 对照

NCBI Gene ID	`LOC130999599`
GeneID	`130999599`
locus_tag	`-`
NCBI Name	`LOC130999599`
原始查询	`SmilChr08G004952`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	E3 ubiquitin-protein ligase SIRP1
产物	E3 ubiquitin-protein ligase SIRP1
Arabidopsis	`AT1G55530` (AT1G55530) RING/U-box superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:842000] identity=51.9; qcov=1.09; evalue=6.85e-111; confidence=high
Rice	`Os03g0812200` (OsRFP) - identity=43.7; qcov=1.06; evalue=3.98e-72; confidence=medium
GO	GO:0005737 (cytoplasm); GO:0016567 (protein ubiquitination); GO:0061630 (ubiquitin protein ligase activity)
KEGG	-
Pfam	PF00097 (zf-C3HC4); PF13639 (zf-RING_2); PF13923 (zf-C3HC4_2); PF14369 (Zn_ribbon_19); PF17123 (zf-RING_11)
InterPro	-
eggNOG	-
NR	GeneID:130999599

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057781155.1`
2	Cytosol	细胞质基质	0.80000	`XP_057781155.1`
3	Nucleus	细胞核	0.20000	`XP_057781155.1`
4	Chromosome	染色体	0.00000	`XP_057781155.1`
5	Centromere	着丝粒	0.00000	`XP_057781155.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:58378210`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B108,C85
`Chr8:58378259`	`GA`	`G`	1bp_deletion	frameshift_variant	1	B136
`Chr8:58378259`	`GA`	`G`	1bp_deletion	CDS_variant	1	B136
`Chr8:58378320`	`GC`	`G`	1bp_deletion	CDS_variant	1	D11
`Chr8:58378439`	`TAA`	`T`	2bp_deletion	frameshift_variant	1	C44
`Chr8:58378439`	`TAA`	`T`	2bp_deletion	CDS_variant	1	C44
`Chr8:58378529`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B55
`Chr8:58378595`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B5,D10
`Chr8:58378918`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B105,B94
`Chr8:58378996`	`C`	`CA`	1bp_insertion	frameshift_variant	77	A11,A2,A21,A23,A6,B10,B102,B105,B106,B11,B117,B118,B120,B123,B125,B130,B132,B133,B138,B139,B14,B140,B16,B21,B29,B31,B32,B33,B36,B41,B54,B56,B58,B59,B6,B64,B67,B71,B72,B73,B76,B77,B8,B80,B82,B84,B88,B9,B94,B96,C10,C16,C21,C23,C27,C28,C29,C30,C39,C40,C44,C45,C48,C50,C52,C54,C58,C59,C65,C67,C72,C82,C9,D4,D5,D6,D7
`Chr8:58379000`	`AG`	`A`	1bp_deletion	frameshift_variant	85	A11,A13,A14,A2,A21,A23,A4,A6,B10,B102,B105,B106,B11,B117,B118,B120,B123,B125,B130,B132,B133,B138,B139,B14,B140,B16,B21,B29,B31,B32,B33,B36,B41,B54,B56,B58,B59,B6,B64,B67,B70,B71,B72,B73,B76,B77,B8,B80,B82,B84,B87,B88,B89,B9,B94,B96,C10,C16,C21,C23,C27,C28,C29,C30,C39,C40,C44,C45,C48,C50,C52,C54,C58,C59,C65,C67,C72,C73,C82,C9,D4,D5,D6,D7,D9

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057781155.1

339 aa

170

339

Zn_ribbon_19

zf-RING_11

zf-C3HC4_2

zf-RING_2

zf-C3HC4

PF14369 Zn_ribbon_19 8-40 aa PF17123 zf-RING_11 232-260 aa PF13923 zf-C3HC4_2 232-273 aa PF13639 zf-RING_2 232-274 aa PF00097 zf-C3HC4 233-273 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057781155.1`	Pfam	`PF14369`	Zn_ribbon_19	Domain	8	40	1.8e-12	47.9	zinc-ribbon
`XP_057781155.1`	Pfam	`PF17123`	zf-RING_11	Domain	232	260	3.9e-08	33.5	RING-like zinc finger
`XP_057781155.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	232	273	5e-08	33.3	Zinc finger, C3HC4 type (RING finger)
`XP_057781155.1`	Pfam	`PF13639`	zf-RING_2	Domain	232	274	6.6e-14	52.6	Ring finger domain
`XP_057781155.1`	Pfam	`PF00097`	zf-C3HC4	Domain	233	273	9.3e-06	26.1	Zinc finger, C3HC4 type (RING finger)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057925172.1
ATGGAGGAAGCTGAGGCACTAAGATATTGGTGCCACATGTGTTCACAGAATGTGAATCCAGTTTTGGAGATTGATACCATAAAATGCCCCATCTGCCAAAGCGGCTTTGTGGAAGAAATGGCCACTCCCACTCCAGAAAATGATAGCCCTCCTGATGTTGAATTCGGAGGGCCGGATTCTGATCGCGCCCTCTCCCTCTGGGCGCCCATCCTACTCGGTATGATGGGCAACCAGCGGCGTAGGCGCCGTATGAGGCGCAT...

CDS

1 records

下载 CDS FASTA

LOC130999599
ATGGAGGAAGCTGAGGCACTAAGATATTGGTGCCACATGTGTTCACAGAATGTGAATCCAGTTTTGGAGATTGATACCATAAAATGCCCCATCTGCCAAAGCGGCTTTGTGGAAGAAATGGCCACTCCCACTCCAGAAAATGATAGCCCTCCTGATGTTGAATTCGGAGGGCCGGATTCTGATCGCGCCCTCTCCCTCTGGGCGCCCATCCTACTCGGTATGATGGGCAACCAGCGGCGTAGGCGCCGTATGAGGCGCAT...

Protein

1 records

下载 Protein FASTA

XP_057781155.1
MEEAEALRYWCHMCSQNVNPVLEIDTIKCPICQSGFVEEMATPTPENDSPPDVEFGGPDSDRALSLWAPILLGMMGNQRRRRRMRRMGYEEGENHHDGESELDRELEAIVRRRRSSAAILQLLQGMRAGILSEPETDQGNDTTDNERERERERVILINPFNQTIIVQGSYDPGNESISRAPIGSLGDYFIGPGLDLLLQHLSENDPNRYGTPPAQKEAVEALPTVEIVDTLQCSVCLDDCDIGDQVKEMPCKHKFHSKCI...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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